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KMID : 1039120200090020179
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Clinical and Experimental Vaccine Research
2020 Volume.9 No. 2 p.179 ~ p.182
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Current national policies for infant universal bacille Calmette-Guerin vaccination were associated with lower mortality from coronavirus disease 2019
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Ebina-Shibuya Risa
Horita Nobuyuki
Namkoong Ho
Kaneko Takeshi
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Abstract
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An exciting debate has emerged whether bacille Calmette-Guerin (BCG) vaccination is effective for the coronavirus disease 2019 (COVID-19) pandemic. Some advocated that BCG-vaccinated people are less suffered from the virus because BCG vaccination is recommendedin COVID-19 high burden countries. However, the others objected because this seemingly attractive relationship is explainable with confounding factors. In a multiple regression with 171 countries adjusting socioeconomical and climatic covariates, countries with current universal pediatric BCG policy were associated with 30-fold (95% confidence interval, 17?52) decrease of COVID-19 mortality per population compared to countries without the policy.
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KEYWORD
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Vaccine, Viruses, Pneumonia, Epidemiology
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